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Euroscreen FAST provides specific GPCR family testing based on your request.
We can profile compounds on large panels of receptors including chemokine, serotonine, neuropeptide, purinergic, fatty acid receptors. Euroscreen FAST also offers functional profiling on GPCRs related to specific therapeutic fields.
Euroscreen FAST offers functional profiling on 40 receptors covering the different classes of GPCR.
Functional profiling of one compound for agonist and antagonist activity
| GPCR |
assay |
Agonist |
Antagonist |
| 5-HT6 |
Aequorin assay |
5-HT |
mianserin |
| Adenosine A3 |
Aequorin assay |
IB-MECA |
MRS1220 |
| Adrenergic a2A |
Aequorin assay |
UK14,304 |
Yohimbine |
| Angiotensin AT1 |
Aequorin assay |
AngII |
[Sar,Ile] AngII |
| bb3 |
Aequorin assay |
D-Tyr Bombesin [6-14] |
D-Phe-bombesin |
| CCK2 |
Aequorin assay |
Sulfated CCK-8 |
|
| CCR2b |
Aequorin assay |
CCL2 |
RS102895 |
| CGRP |
Aequorin assay |
Human CGRP |
B10647603 |
| ChemR23 |
Aequorin assay |
Chemerin 9 |
|
| CRF1 |
Aequorin assay |
Human urocortin |
|
| CX3CR1 |
Aequorin assay |
CX3CL1 |
|
| CXCR2 |
Aequorin assay |
CXCL8 |
SB225002 |
| ETA |
Aequorin assay |
ET-1 |
BQ123 |
| FPRL1 (ALX) |
Aequorin assay |
w-peptide |
|
| GAL2 |
Aequorin assay |
Human galanin |
|
| GHS-R |
Aequorin assay |
Ghrelin |
D-Lys-GHRP6 |
| GPR43 |
Aequorin assay |
propionate |
|
| H3 |
Aequorin assay |
Histamine 2HCl |
Thioperamide |
| KISS1 |
Aequorin assay |
Metastin |
|
| MCH1 |
Aequorin assay |
human MCH |
ATC0175 |
| Melatonin MT1 |
Aequorin assay |
I-melatonin |
luzindole |
| MrgX1 |
Aequorin assay |
BAM-22P |
|
| Muscarinic M3 |
Aequorin assay |
Acetylcholine |
4-DAMP |
| NK2 |
Aequorin assay |
NKA |
SR48968 |
| NPFF2s |
Aequorin assay |
Human NPFF |
|
| OXER1 |
Aequorin assay |
5-OXO-ETE |
|
| P2Y11 |
Aequorin assay |
ATPgS |
NF157 |
| PAR2 |
Aequorin assay |
Trypsin |
|
| S1P5 (edg8) |
Aequorin assay |
S1P |
|
| sst2 |
Aequorin assay |
Somatostatin 28 |
|
| Urotensin-II |
Aequorin assay |
Human urotensin |
|
| Apelin |
GTPgS |
Apelin 13 |
|
| BLT1 |
GTPgS |
LTB4 |
LY255283 |
| CB1 |
GTPgS |
CP55940 |
AM251 |
| Dopamine D3 |
GTPgS |
Dopamine |
|
| GABAB 1A |
GTPgS |
SKF97541 |
CGP54626 |
| MOP-OP3 |
GTPgS |
DAMGO |
CTOP |
| N/OFQ (NOP) |
GTPgS |
Human nociceptin |
|
| Prostanoid CRTH2 |
GTPgS |
PGD2 |
BWA866c |
| RX3 (GPCR135) |
GTPgS |
Relaxin 3 |
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