Euroscreen S.A.

Jean Combalbert, PhD; Chief Executive Officer.

Jean Combalbert joined Euroscreen with more than 15 years experience in pharmaceutical and biotech companies. Jean received his PhD in Pharmacy from the University of Marseille, France. After his Ph.D. on pharmacokinetics and metabolism in French public research (INSERM), he joined the pharmaceutical industry where he had senior positions with Sanofi in Montpellier then with Galderma successively based in Sophia Antipolis, France, and then in Princeton, NJ, USA. Prior to joining Euroscreen, he was Chairman & CEO of Entomed SA, of Strasbourg, France.

Graeme Fraser, PhD; Director, Drug Discovery

Graeme Fraser joined Euroscreen with more than 14 years of industry experience in both management and technical positions. Previously, Graeme was V.P., Drug Discovery at Tranzyme Pharma (Sherbrooke, Canada) where he led the discovery and preclinical development activities for a pipeline of GPCR-small molecule programs. Earlier, he managed preclinical development activities at Viron Therapeutics Inc. (London, Canada) and led specific GPCR target validation activities at Astra Pain Control AB (Södertälje, Sweden and Montreal, Canada). In total, he has directed research activities for three products currently in clinical development. Graeme received a Ph.D. from McGill University (Montreal, Canada) and is an author of over fifty publications and research abstracts, including nine patents and two IND filings.

Al Gray, PhD; Director, Business Development

Al Gray has been responsible for business development at Euroscreen since 1999. His previous positions were at Abbott Laboratories where he served for 22 years in pharmaceutical and diagnostic research, development, strategic planning and partnering experience, and as the founder of Recombinant Capital Europe AG, in Basel from 1998 to 2001. He received his Ph.D. in biochemistry from Northwestern University. Postdoctoral years were spent at Brandeis University and the University of Illinois Medical Center, specializing in immunology and protein biochemistry.

Michel Detheux, PhD; Director, Euroscreen Fast Business Unit

Michel Detheux is managing director for services activities. He joined Euroscreen in 1995 to develop new technologies. In 1998, he set up the target discovery group and managed it until 2004. In 2005, he moved into new business opportunities, then in 2006 into services activities as Business Unit Director. He received his PhD in Biochemistry from the Catholic University of Louvain, Belgium and also received a Certificate in Business from Solvay Business School in 2002.

In addition more than 15 PhDs with diversified industry experience are directly managing lab activities.